摘要
目的建立碳酸氢钠注射液细菌内毒素检查方法。方法参照《中国药典》2005年版(二部)附录细菌内毒素检查法及其指导原则进行试验。结果干扰实验表明供试品稀释4倍可消除干扰。结论碳酸氢钠注射液细菌内毒素检查法可代替家兔法热原检查。
Aim To establish a bacterial endotoxin test for sodium bicarbonate injection. Methods According to the ChP 2005 Edt. ,inhibition or enhancement test for bacterial endotoxin test was carried out of sodium bicarbonate injection. Result The injection did not interfere with the limulus agent in 4 times diluted concentration. Conclusion Bacterial endotoxin test may be used for quality control of sodium bicarbonate injection.
出处
《安徽医药》
CAS
2008年第1期24-26,共3页
Anhui Medical and Pharmaceutical Journal
关键词
碳酸氢钠注射液
细菌内毒素检查
干扰试验
sodium bicarbonate injection
bacterial endotoxin test
inhibition or enhancement test
