摘要
目的建立氯霉素滴眼液中氯霉素含量的测定方法。方法采用一阶导数分光光度法,样品不经分离处理直接测定氯霉素滴眼液中氯霉素的含量,检测波长为300nm。结果线性范围为8～64mg/L,r=0.9998,平均回收率为99.9%,RSD为1.2%。结论该法可消除其他组分的干扰,简便易行,适合作为氯霉素滴眼液的质量控制。
Objective To establish a method to determine the content of Chloramphenicol eye drops. Methods The first order derivative spectropbotometry was used to determine the cblorampbenicol in cbloramfenicol eye drops, without separation. The detecting wavelengb was at300 nm. Results The method was linear within range8 - 64 mg/L, r = 0. 999 8. The average recovery of chloramphenicol was 99.9% and RSD was 1.2%. Conclusion The interference of the other components can be excluded by this method;which is simple, rapid. It is suitable for the quality control of Cblorampbenicol eye drops.
出处
《中国实用医药》
2008年第3期12-13,共2页
China Practical Medicine
关键词
一阶导数光谱法
氯霉素
滴眼液
First order derivative spectrometry
Chloramphenicol
Eye drops
