摘要
观察皮下埋植左旋-18甲基炔诺酮(LNG)术后用雌激素处理对 SD 鼠子宫内膜、卵巢组织ER、PR 含量的影响。用饱和浓度单点法测定皮埋术后用雌激素处理的 SD 鼠子宫内膜、卵巢组织ER、PR 含量。分未处理组、皮埋对照组、皮埋配伍雌激素组和皮埋配伍生理盐水对照组。结果显示:雌激素处理组子宫内膜、卵巢组织 ER、PR 含量较同期对照组显著升高(P<0.01),但与用药时间长短无关。该组雌性大鼠与成年雄性大鼠合笼,无一例受孕。提示用雌激素可减少皮埋术引起的子宫内膜、卵巢组织 ER、PR 含量的下降。
Estrageon on the contents of ER and PR in the en- dometrium and Ovary of rats after Norplant treatment was studied.Method:The sigle-point method in satu- ration was used for the measurement of ER and PR con- tents.We designed 4 groups:LNG control group(A group),black control group(NS),LNG and DES group (B group),LNG and NS group(C group).The results showed that ER and PR contents in B group were significantly increased more than those in A group(P< 0.01).These contents were not increased gradually with the time lengthen of implantation.No pregnancy hap- pened after putting those female rats of B group with male rat for 10～40 days.Conclusion:Estrogen may in- crease the ER and PR concentrations in the endometri- um and ovary in rats,which were reduced by Norplant.
出处
《中国计划生育学杂志》
1997年第4期208-209,211,共3页
Chinese Journal of Family Planning
