摘要
目的：报告２７例以垂体腺瘤为主要表现的多发性内分泌腺瘤病人的临床表现及诊断、治疗情况，对其发病机制、早期诊断及临床治疗原则等进行了讨论以便取得较好的疗效。方法：回顾性的总结了２７例以垂体腺瘤为主要表现的多发性内分泌腺瘤病人的病史、临床表现及诊断、治疗情况，结合文献加以分析和总结。结果：除１例ＰＲＬ腺瘤病人服用溴隐亭治疗外均行垂体腺瘤切除术，治疗效果满意，无明显手术并发症，无死亡。其它腺体肿瘤亦行手术切除治疗，良性肿瘤预后较好，恶性肿瘤，如类癌、甲状腺癌等预后较差。结论：早期诊断早期治疗是提高疗效的关键。对于多发性内分泌腺瘤患者，无论是垂体腺瘤还是其它腺体肿瘤，均以手术治疗为主，必要时辅以放射治疗和化学药物治疗，可以取得良好疗效。
Objective: To improve therapeutic effevtiveness for patients with multiple endocrine neoplasia type 1 (MEN 1). Methods: 27 MEN 1 patients with main manifestation of pituitary adenoma were reviewed in this paper. The diagnosis, clinical features, and principle of treatment were discussed. Result: The pituitary adenoma was removed by transfrontal or transsphenoidal procedure operation except one PRL adenoma's patient who treated by bromocriptin, Good results were got. Conclusion: Early diagnosis and treatment are very important for MEN 1 patients.
出处
《中华神经外科杂志》
CSCD
北大核心
1997年第4期208-210,共3页
Chinese Journal of Neurosurgery
