摘要
目的:对通心络胶囊治疗冠心病心绞痛的疗效及安全性作出评价。方法:采用随机对照,治疗组342例给予通心络胶囊(4粒,每日3次),对照组150例给予舒心口服液(20ml,每日2次)。4周后进行心绞痛、心电图、主要症状、总疗效及毒副作用评估。结果:治疗组心绞痛总有效率96.49%明显优于对照组78.00%(P<0.01);治疗组心电图总有效率71.05%明显优于对照组47.33%(P<0.01);治疗组对轻、中、较重度患者均有很好疗效。结论:通心络胶囊治疗冠心病心绞痛疗效确切,无毒副作用。
Objective;To observe the effects of Tongxinluo capsule(TXLC)in treating angina pectoris(AP)caused by coronary heart disease(CHD)and evaluate its safety.Methods;Randomized single-blind controlled design were adopted.Three hundred and forty two patients were treated with TXLC(4 capsules,three times daily),and 150 patients in the control group done with Shuxin oral liquor(SXOL,20ml,two times daily).After 4 weeks of treat-ment,the data of AP,ECG,main-symptoms,total effects were coliected and evaluated.Results:TXLC appeared to be more effective than SXOL for patients with mild,moderate,severe AP(P<0.01),except with mild storn-ach discomfort for a few patients,TXLC has no side effect and toxicity.Concluslon:TXLC is en effective drug in treating AP and has no side effectsand toxicity.
作者
徐贵成
高荣林
吴以岭
刘俊玲
高学东
李辉
XU Gui-cheng;GAO Rong-lin;WU Yi-ling(Guang'anmen Hospital.China Academy of Tra-ditional Chinese Medicine,Beijing,100053)
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1997年第7期414-416,共3页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
通心络胶囊
胸痹
冠心病
心绞痛
Tongxinluo capsule
Xiong-bi(obstruction of Qi in the chest)
coronary heart disease
