摘要
目的 观察通心络胶囊对不稳定型心绞痛患者 von Willebrand 因子(vWF)和纤维结合蛋白(Fn)水平的影响,并探讨其治疗机制。方法 60例不稳定型心绞痛(UAP)患者,随机分为常规组和通心络组,前者给予常规扩冠、抗血小板聚集治疗,后者在常规治疗基础上加用通心络胶囊4粒,每日3次,并于服药前后分别抽血测定血中vWF和Fn水平变化。结果 通心络组患者治疗后血中vWF和Fn水平明显回落,且通心络组总有效率明显高于常规组(P<O.05)。结论 通心络胶囊具有一定保护血管内皮、抑制血小板聚集作用。
Objective To observe the influence on von Willebrand.factor and fibronectin in patients with Tongxinluo capsule and to probe its mechanisms.Methods 60 patients with unstable angina pectoris were randomly divided into common group and Tongxinluo group, the former was treated by vasodilator and platelet adhesion inhibitor, the latter was added Tongxinluo capsule oral based on aforesaid therapy. Plasma vWF and Fn were measured before and after treatment. Results The effective rate is higher in Tongxinluo group than that of common group ( P < 0.05),and the plasma level of vWF and Fn were settle down after Tongxinluo treatment( P < 0.01). Conclusion Tongxinluo capsule have the action of protecting the endothelial cells and inhibiting the platelet adhesion.
出处
《疑难病杂志》
CAS
2002年第2期69-70,共2页
Chinese Journal of Difficult and Complicated Cases
