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中药乐脉颗粒治疗冠心病的临床研究 被引量:1

CLINCAL STUDY ON CORONARY HEART DISEASE TREATED WITH LEMETGRANULE(IMG) PREPARED FROM SEVERAL CHINESE HERBAL MEDICINES
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摘要 用乐脉颗粒对54例冠心病患者进行为期4周的观察治疗,结果表明:稳定型和不稳定型心绞痛发作频率、持续时间均减少(P<0.001)。TG、LDL-C降低分别达28.92%、20.91%(P<0.05).而HDL-C升高19.44%(P<0.05)。血液流变学指标ηp和EPT分别降低10.30%和14.26%(P<0.01);ηb和Fibg降低为4.32%和6.54%(P<0.05).用药后未见明显毒副作用. Fifty four patients with coronary heart disease (CHD) were treated with le Mei gran-ule(LMG), which was prepared from several chinese herbal medicines, for 4 weed. The results showed that both the occurrence frequence and duration of stable or unstable angina of CHD were markedly decreased(P< 0.01 ). After the treatment of LMG, serum total cholesterol (TG) and low density lipoprotein cholesterol(LDL-C) were reduced by 28. 9% and 20. 91% (P<0.05, respectively.High density lipoprotein Cholesterol(HDL-C) was elevated by 19.44% (P<0.05). In the hemorrhe-ology determine, ηp and EFT wre depressed by 10. 30% and 14. 26%respectively (P<0.01). The reduction rates of ηb and Fibg in CHD seperately were 4. 32% and 6.54% (P<0.05). No severe side effect was found in the couse of therapy with LMG. These findings indicate that LMG may be used as an ideal drug in treatment of CHD.
出处 《皖南医学院学报》 CAS 1997年第1期19-21,共3页 Journal of Wannan Medical College
关键词 冠心病 乐脉颗粒 中医药疗法 coronary disease lipids drugs, Chinese herbel
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