摘要
目的 :采用龟鹿二仙胶加味治疗绝经后妇女不稳定型心绞痛的临床研究。方法 :观察患者用药前后心绞痛每天发作次数 ,心电图 2 4h缺血总负荷、E2 、NO、LDL C等指标有无改善。结果 :两组患者用药前后心绞痛每天发作次数、心电图 2 4h缺血总负荷、E2 、NO、LDL C等指标改善有显著意义 (P <0 .0 5或P <0 .0 1) ,中药组在停用或减服抗心绞痛药物的情况下与西药组比较 ,降低心绞痛发作次数及改善心肌缺血仍无显著差异 (P >0 .0 5) ,提高患者E2 、降低LDL C方面与尼尔雌醇相类似 (P >0 .0 5) ,提高NO水平优于西药组 (P <0 .0 5)。结论
Objective:To observe the therapeutic effect of supplemented Guilu Erxian Jiao on menopausal women's unstable angina pectoris.Method:To survey anginal times of cases every day before and after administration,dynamic electrocardiogram,the level of E 2,NO,LDL C,etc in serum.Result:Anginal times,dynamic electrocardiogram,the level of E 2,NO,and LDL C in serum in each group had significant improvement after treatment(P<0.05 or P<0.01).Anginal times and myocardial ischemia hadn't significant difference between western medicine group and TCM group in which the anti angina drugs were withdrawn or the dosage of it was reduced.It showed that supplemented Guilu Erxian Jiao had the same effect as that of nylestriol on improving the level of E 2 and descending the content of LDL C in serum,but the concentration of NO in serum between two groups after 6 months course of treatment was significantly different(P<0.05).Conclusion:Supplemented Guilu Erxian Jiao had effects of relieving menopausal women's unstable angina pectoris and delaying senility.
出处
《安徽中医学院学报》
CAS
2000年第4期20-22,共3页
Journal of Anhui Traditional Chinese Medical College