摘要
目的建立控制肝愈胶囊的质量标准。方法对肝愈胶囊中主要成分丹参、栀子、黄柏、黄芪、五味子进行了薄层色谱鉴别；采用高效液相色谱法测定黄芩苷的含量。结果薄层色谱法可以对该制剂中的丹参、栀子、黄柏、黄芪、五味子作出准确鉴别；黄芩苷的线性范围为0．12～0．58μg，r=0．9997，平均加样回收率为99.06，RSD为1．40（n=5）。结论方法灵敏、简便、重现性好，可作为该制剂的质量标准。
Objective To establish the quality standard for Ganyu Capsule. Methods Radix Salviae Miltiorrhiae, Fructus Gardeniae, Cortex Phellodendri, Radix Astragali and Fructus Schisandrae were identified by TLC. Baicalin was determined by HPLC. Results TLC spots developed were fairly clear, and the blank test showed no interference. Baicalin showed a good linear relationship in the concentration range of 0. 116 8 -0.584 0 μg,and the average recovery was up to 99.06%, RSD was 1.4%. Conclusion The method is accurate, reproducible and simple. It can be used as the quality control of this preparation.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2007年第11期2716-2718,共3页
Lishizhen Medicine and Materia Medica Research
基金
黑龙江省科技攻关资助项目(NoGB03C501-2)
