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腹腔镜卵巢子宫内膜囊肿剥除术后卵巢功能的研究 被引量:5

The Study about the Ovarian Function after Laparoscopic Ovarian Cystectomy for Endometriomas
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摘要 目的了解腹腔镜下卵巢子宫内膜囊肿剥除术对残余卵巢功能的影响。方法从我院体外受精一胚胎移植(IVF—ET)数据库中回顾性选取两组病例:研究组70例(A组)曾行腹腔镜下卵巢子宫内膜囊肿剥除术,包括39例单侧卵巢子宫内膜囊肿患者(Al组)和31例双侧卵巢子宫内膜囊肿患者(A2组)。对照组92例(B组)为输卵管性不孕患者。比较IVF—ET周期中的卵巢反应性。结果研究组和对照组的年龄分布和男性不孕的比例相似,前者在IVF—ET周期中的促性腺激素的用量明显高于后者(P<0.001),而HCG注射日的血清雌二醇浓度、优势卵泡数和获卵母细胞数均显著少于后者(P<0.001)。Al组HCG注射日的血清雌二醇浓度、优势卵泡数和获卵母细胞数均多于A2组,但统计学分析差异无显著性(P>0.05)。A1组手术侧卵巢与正常侧卵巢比较,手术侧卵巢的优势卵泡数和获卵母细胞数均显著少于正常侧卵巢(P<0.05)。结论腹腔镜下卵巢子宫内膜囊肿剥除术对卵巢功能有一定的影响。 Objective To learn the effects of lapropic cystectomy of endometriomas on the ovarian of the residual ovary.Methods Two groups of patients v-ere retrospectively selected from an in vitro fertilizatiun-embryo transfer (TVF-ET) database in our hospiral: 70 patients who underwent laparoseopic ovarian cystectomy for endometriomas were selected in the study group ( Group A), including 39 unilateral endometrions patients ( Group AI ) and 31 bilateral endometriomas patients ( Group A2) ; 92 patients vdth tubal infertility were taken as control group (Group B). The ovarian in response during IVF-ET cycles were compared. Results 'The age distribution and the percentage of male infertility were similar betweon Group A and Group B, the number of gonadotropin ampeules in IVF-ET cycles in Group A was significantly higher than in Group B (P 〈 0.001 ), but the blood E (2) concentration and the numbers of dominant follicle observed on the day of hCG injection and the numbers of oocytes retrieved in Group A were signilfcanfly less than in Group B (P〈 0.001). The blood E (2) concentration, the numbers of dominant follicle observed on the day of, hCG injection and the numbers of oocytes retrieved in Group AI were higher than in Group A2, but there were no significantly statistical differences ( P 〉 0.05). In Group A1, operated ovaries were compared with contralateral intact ovaries of the same patient, the nunbers of dominant follicle and oocytes retrieved in operated ovary were significantly less than in intact ovary (P 〈 0.05 ). Conclusions Lapawseopic ovarian cystectomy for endometriomas had bad effect on the ovarian function.
出处 《浙江预防医学》 2007年第11期8-9,12,共3页 Zhejiang Journal of Preventive Medicine
关键词 卵巢子宫内膜囊肿 腹腔镜手术 卵巢功能 体外受精-胚胎移植 Endometriomas Laparoscopy Ovarian fimction In vitro fertilization-embryo transfer
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  • 1Alborzi S,Momtahan M,Parsanezhad ME,et al.A prospectire,randomized study comparing laparoscopic ovarian cystectomy versus fenestration and coagulation in patients with endometriomzs[J].Fertil Steril,2004,82 (6):1633-637.
  • 2Somigliana E,Ragni G,Benedetti F,et al.Does laparoscopic excision of endometriotic ovarian cysts significantly affect ovarian reserve?Insights from IVF cycles[J].Hum Reprod,2003,18 (11):2450-2453.
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  • 6王世阆.卵巢手术应注意的问题(二)(卵巢囊肿剔除术)[J].实用妇产科杂志,2005,21(1):62-63. 被引量:20

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