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卵巢储备功能监测研究进展与卵巢早衰的预测 被引量:67

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摘要 卵巢早衰(POF)指40岁以前出现绝经,并呈低雌激素(E)水平和高促性腺激素血症状态,发病率约为1%[1]。目前临床常用的生化指标检测是卵泡刺激素(FSH)、黄体生成激素(LH)的升高,E水平的降低,尚缺乏能够早期预测和诊断POF的确切指标。随着生殖医学的发展,对卵巢储备功能的研究越来越深入。卵巢储备功能是指卵巢内存留卵泡的数量和质量,反映女性的生育能力;卵巢产生卵子能力减弱,卵泡细胞质量下降,导致生育能力下降,称卵巢储备能力下降。卵巢储备能力下降,有可能发展为卵巢功能衰竭。因此,早期发现卵巢衰竭倾向,可以延缓甚至逆转POF。现就卵巢储备功能监测研究进展在POF的预测及诊断中的应用做如下综述。
出处 《国外医学(计划生育分册)》 CAS 2005年第5期257-261,共5页
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