摘要
目的：观察沙棘抗缺血性快速性室性心动过速（室速）的疗效。方法：将１０２例合并室速的冠心病患者随机分为２组，治疗组（４６例）应用莫雷西嗪（ＭＣＺ）加沙棘，对照组（５６例）单用ＭＣＺ。治疗３周。结果：治疗组对室性早搏（室早）、室速显效率６５．２％，有效率２６．１％，总有效率９１．３％，明显高于对照组（４２．９％，１７．９％和６０．７％，Ｐ均＜０．０１）。结论：沙棘能增强ＭＣＺ的抗室性心律失常作用，并有显著改善血液流变性、降低血脂、调理血脂蛋白及改善临床症状的作用，尤其适用于缺血性心脏病伴快速性室性心律失常患者。
Objective:To observe the therapeutic effects of hippophae rhamnoides in treatment of ischemic ventricular tachycardia.Methods:One hundred and two cases of coronary heart disease (CHD) with complication of ventricular tachycardia were randomly divided into two groups.Fortysix cases in the treatment group were administered with both moracizine and hippophae rhamnoides and 56 cases in the control group were administered with moracizine solely.Results:Administered for 3 weeks,there were significant differences between the treatment group(significant effective rate was 65 2%,effective rate was 26 1%,total effective rate was 91 3%)and the control group(42 9%,17 9% and 60 7% respectively) in treating ventricular premature and ventricular tachycardia(all P <0 01).Conclusions:Hippophae rhamnoides can enhance the antiarrhythmic actions of moracizine,improve hemorrheology significantly,decrease the serum lipid level,modulate the serum lipoproteins and control clinical symptoms,especially for patients of ischemic heart disease complicated with ventricular arrhythmia,it is worth to extend in clinical practice.
关键词
沙棘
莫雷西嗪
缺血性
室性心律失常
hippophae rhamnoides\ \ moracizine\ \ ischemic heart disease\ \ ventricular arrhythmia
