摘要
目的:探讨植物神经功能与冠状动脉粥样硬化性心脏病(简称冠心病)患者室性心律失常的关系。方法:对我院126例进行了动态心电图检查及心率变异性(heartratevariability,HRV)分析的冠心病患者的室性心律失常和HRV指标进行回顾性分析。并应用Logistic回归筛选冠心病患者室性心律失常的HRV预测指标。结果:HRV各项时域指标和频域指标中的LF、VLF、HF均有随着室性心律失常程度的加重而降低的趋势,时域指标中的SDNN、SDANN、ASDNN、PNN50b与室性心律失常程度呈弱负相关(P<0.01或P<0.05)。Logistic回归结果表明SDANN为冠心病患者室性心律失常的保护因素。结论:HRV与冠心病患者室性心律失常程度呈弱负相关,SDANN为冠心病患者室性心律失常的保护因素。早期对植物神经功能紊乱进行干预治疗,可能有利于减少冠心病患者室性心律失常的发生。
Objective To analyze the relationship between autonomic nerves and ventricular arrhythmia in patients with coronary heart disease （CHD）. Methods One hundred and twenty-six patients with CHD having been monitored by Hoher（dynamic electrocardiogram, D-ECG） were retrospectively selected. The correlation between heart rate variability （HRV） and ventricular arrhythmia were analyzed. HRV indices to forecast ventricular arrhythmia were screened out by stepwise muhinomial ordinal logistic regression, Results Both time and frequency domain indices （LF,VLF,HF） had a decreasing trend with ventricular arrhythmia. There were weak negative correlation between time domain indices （SDNN, SDANN, ASDNN or PNN50b） and ventricular arrhythmia （P 〈 0.01 or P 〈 0.05）. The result of logistic regression indicated that SDANN was protective factor. Conclusions There are weak negative correlation between HRV and the severity of ventricular arrhythmia in patients with CHD. SDANN is protective factor of ventricular arrhythmia. It is in favour of reducing ventricular arrhythmia if the disorders of autonomic nerves could be treated earlier.
出处
《实用医学杂志》
CAS
2007年第21期3341-3343,共3页
The Journal of Practical Medicine
