摘要
分析46例行冠状动脉造影术（CAG）患者的临床、血管造影资料和心率变异（HRV）情况，探讨冠状动脉（冠脉）病变和HRV的关系。根据临床及血管造影结果分为：无心肌缺血及CAG正常者为N组，有心肌缺血存在而CAG示无冠脉狭窄或狭窄＜50％者为X组，有心肌缺血表现及冠脉狭窄≥50％者为S组。结果：3组患者的基本情况（包括陈旧性心肌梗塞、心功能、舒张期左室内径、血脂、血压、吸烟、服药情况）均无明显差异；S组和X组24小时平均R－R间期均轻度缩短，两组的迷走神经张力（HF）均明显降低，S组降低更明显，两组相对性交感神经活性（LF／HF）均高于N组，以S组升高更显著。提示：冠心病患者均有程度不等的迷走神经功能下降，冠脉狭窄明显组比无或轻度狭窄组下降更明显，与冠心病的危险因素、左心功能、陈旧性心肌梗塞及药物影响无关。推测冠心病患者的迷走神经张力下降和冠心病的其他易患因素一样，为冠心病发病的重要原因。
Coronary angiography(CAG)was performed in 46patients in whom the clinical and angiographic data andthe heart rate variation (HRV)were analyzed, and therelationship between the coronary lesion and HRV wasstudied. According to the clinical and angiographicfindings, the patients were divided into the followinggroups: (1 ) group N: normal CAG without myocardialischemia; (2) group X: CAG showed coronary stenosis(coronary lumen decreased by < 50% ) or no stenosiswith the existance of myocardial ischemia ; (3)group S:there were coronary stenosis (lumen decreased by ≥50% ) and manifestations of myocardial ischemia. Theresults showed: (1) no differences in the basic condition(including old myocardial infarction, heart function,diastolic left ventricular internal diameter, bloodlipid, blood pressure, smoking, and medication )betweenthe patients of the three groups; (2) in group S andgroup X, the average R - R intenval of 24 hours wasslightly decreased,and HF(particularly in group S)obviouslydecreased; (3) LF/HF was greater in group Sand group X than that in group N. It is suggested thatdifferent degrees of vagal depression are seen in patientswith coronary heart disease (CHD),and the depressionis more significant in those with obvious coronary stenosis than those without or with mild stenosis,but it is not related to the risk factors of CHD, leftheart function, old myocardial infarction and medication.
出处
《中国危重病急救医学》
CAS
CSCD
1996年第7期398-400,共3页
Chinese Critical Care Medicine
关键词
心率变异
冠脉造影
心脏病
冠心病
coronary heart disease
heart rate variation
coronary angiography
