摘要
目的:研究冠心病并抑郁症患者心率变异性(HRV)的变化。方法:将临床确诊为冠心病的120例患者分为抑郁组与非抑郁组以及急性冠脉综合征(Acs)组与非ACs(Non-ACs)组,了解抑郁与非抑郁冠心病患者的HRV变化,比较不同冠心病分型中HRV改变,以及抑郁与HRV的相关性。结果:冠心病并抑郁患者中抑郁组时域指标SDNN、SDANN、SDNNDX、RMSSD及PNN50均显著低于非抑郁组(P<0.01或0.05);抑郁组频域指标VLF及LF显著高于非抑郁组(P<0.01),而HF显著低于非抑郁组(P<0.05)。ACS组时域指标SDNN、SDANN、SDNNDX、RIdSSD及PNN50均显著低于Nono-ACS组(p<0.05);AcS组频域指标VLF、LF显著高于Non-ACS组(p<0.05)。抑郁严重度指数与心率变异性各指标相关。结论:冠心病合并抑郁患者心率变异性发生改变且抑郁与心率变异性相关。
Objective：To investigate the depression heart rate variability（HRV）in patients with coronary artery disease（CHD） complicated by depression.Methods： 120 patients were divided into depression group （n=64） and non-depression group（n=56）;ACS group（n=59） and Non-ACS group（n=61）.The HRV variation and correlation between depression and HRV were analysed in the CHD patients complicated by depression.Compared HRV between different type of CHD.Results：The SDNN,SDANN,SDNNDX,RMSSD,PNN50 and HF were lower, VLF and LF were higher in non-depression group.The SDNN,SDANN,SDNNDX,RMSSD,PNN50 and HF were lower and VLF, LF were higher in Non-ACS group.Depression seriousness index correlated with all of the HRV index.Conelusion：HRV has changed and correlates with depression in the CHD patients complicated by depression.
出处
《中国医药导刊》
2010年第7期1145-1147,共3页
Chinese Journal of Medicinal Guide
关键词
抑郁
冠心病
心率变异性
Depress
Coronary artery disease
Heart rate variability
