摘要
目的:利用高频血管超声技术评价心脑血管患者外周动脉结构的变化及主要危险因素。方法:①对1266例受检者应用血管超声观察双侧颈动脉、腹主动脉、股动脉内膜一中膜厚度、斑块形成情况;②对其中534例心脑血管疾病患者,同时测定血清总胆固醇(TC)、甘油三脂(TG)、低密度脂蛋白(LDL)、血清胰岛素及空腹与餐后血糖、血清胆红素等。正常体检247例为对照组。结果:①大血管病变中以颈动脉内膜异常最常见,占所检血管的88.4%;②观察组双侧颈动脉、股动脉、腹主动脉内一中膜厚度、斑块形成显著高于对照组(P<0.05);③多元逐步回归分析显示年龄、收缩压、餐后高血糖、甘油三脂是高海拔地区大血管损害的独立危险因素,血清胆红素为大血管损害保护因素。结论:应用高频超声技术可动态评价外周动脉管壁结构的变化,年龄、餐后高血糖、收缩压、甘油三脂、血清胆红素与老年人大血管损害密切相关。
Objective： To observe the changes of peripheral atherosclerosis and its dangerous factors in Cardiovascular and cerebrovascular disease with high frequency ultrasound. Methods： ①Vascular ultrasound were applied to measure both sides carotid artery.abdominal artery, femoral artery intima-media thickness （IMT） and its plaques in 1 266 subjects. ②The level of total cholesterol（TC）, blood triglyceride （TG）, low density lipoprotein cholesterol（LDL） and fasting glucose （IFG） were measured in 534 of subjects after meal glucose, insulin and serum bilirubin; 247 healthy subjects served as controls. Results： ①Carotid artery intima-media thickness was higher than others. ② All artery intima-media thickness（IMT） and its plaques were greater（P〈0. 05）in the sickness group compared with the controls. ③Multiple regression stepwise analysis revealed that ages, systolic blood pressure, triglycerides were the independent risk factors, and serum bilirubin was just protective factor. Conclusions： The changes of the peripheral vascular construction can be evaluated using the high frequency ultrasound. There are significant correlations between the artery injury and ages, systolic blood pressure, postprandial hyperglycemia, triglycerides and serum bilirubin.
出处
《高原医学杂志》
CAS
2007年第3期28-31,共4页
Journal of High Altitude Medicine
关键词
血管超声
外周动脉疾病
西宁地区
Ultrasonography
Peripheral artery disease
High altitude
