摘要
目的:观察不同剂型氢氧化钙通过模拟根管向根尖周扩散的效果。方法:用吸液管尖、BHI琼脂及5ml塑料注射针筒制备成模拟根尖周模型。120个模型分为3组,每组40个,按根尖孔径不同(15#、25#、40#、80#),每组又分为4个亚组,每亚组10个。第1组模拟根管内封入20%氢氧化钙悬浊液100μl;第2组封入90%氢氧化钙糊剂100μl;第3组封入氢氧化钙药尖并加入100μl蒸馏水。另备12支模拟模型,封入100μl蒸馏水作为对照。用pH分析仪和钙离子分析仪分别测定pH值和Ca2+浓度。将所得数据建立数据库,采用SPSS13.0软件包进行随机区组设计的方差分析。结果:pH分析发现,第1、2、3组的平均pH值分别为8.26、7.96和7.83,第1组与2、3组之间有显著性差异(P<0.05),第2、3组之间平均pH值无显著差异;Ca2+测定结果,第1、2、3组平均Ca2+浓度分别为29.87、24.62和16.42ppm,3组间均有显著性差异(P<0.05)。分析结果还表明,不同根尖孔径平均pH值和平均Ca2+浓度组间均有显著性差异(P<0.05),依次为80#>40#>25#>15#。结论:氢氧化钙悬浊液在模拟根尖周模型内的扩散效果好于氢氧化钙糊剂和氢氧化钙药尖;根尖孔径越大,药物扩散效果越好。
PURPOSE： To investigate the diffusion effect of calcium hydroxide in periapical simulation of the diffusion model. METHODS： Pipetman pipette tips ,plastic syringes and BHI agar were prepared to be periapical simulation of the diffusion model. 120 simulation models were divided into three groups. Group 1： 100μl 20% calcium hydroxide suspension were sealed in pipette tips; group 2 ： 100μl 90% calcium hydroxide cataplasm were sealed in; group 3： 100μl calcium hydroxide points were sealed in. By different apical aperture （15#,25#,40#,80#）, each group was divided into four subgroups （each subgroup contained 10）. Preparation of 12 other simulation models sealed with distilled water were as a control, pH values and Ca^2＋ concentration were measured by PH analyzer and calcium analyzer respectively.The data was collected to establish a database , using SPSS13.0 software package, randomized block design ANOVA was performed. RESULTS： The average pH value （8.26, S=0.86） of group 1 was significantly higher than that in group 2 （7.96, S=0.702） and Group 3 （7.83, S=0.59） （P〈0.05）, but no significant difference was found between group 2 and group 3.The average calcium concentration of group 1 （29.87ppm. S=10.76） was significantly higher than that in group 2 （24.62ppm. S=10.40） and group 3（16.42ppm, S=5.70）. There were significant differences among the three groups （P〈0.05）. The results also showed that the average pH value and the average calcium concentration were increased with apical aperture.There were significant differences between each group （P〈0.05）. CONCLUSION： The diffusion effect of calcium hydroxide suspension in periapical simulation of the diffusion model is better than calcium hydroxide cataplasm and calcium hydroxide points; the diffusion effect is also proportional to the apical aperture. Supported by Key Research Project of Science and Technology Bureau of Sichuan Province（Grant No.05SG022-007）.
出处
《上海口腔医学》
CAS
CSCD
2007年第5期523-526,共4页
Shanghai Journal of Stomatology
基金
四川省科技厅重点项目(05SG022-007)
