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长效β_2-受体激动剂及吸入糖皮质激素联合治疗COPD的研究进展 被引量:7

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摘要 慢性阻塞性肺疾病(COPD)是一种以进行性,不完全可逆性气流受限为特征的慢性炎症性呼吸系统疾病。COPD包括气道炎症、气流受限、粘液纤毛功能障碍和气道结构的改变,这些改变导致COPD患者肺功能下降,呼吸困难等症状以及病情的恶化。气流阻塞和气道炎症关系密切,气道炎症增多的主要炎症细胞为CD8T细胞、巨噬细胞和中性粒细胞,参与的炎症介质有LTB4、IL-8、TNF0633等。近年来,大量实验研究证明。通过针对COPD各种不同的发病环节,长效β2-肾上腺素受体激动(LABA)与吸入糖皮质激素(ICS)联合使用能有效的控制病情。本文综述上述联合治疗COPD的研究进展。
出处 《海南医学》 CAS 2007年第11期171-173,共3页 Hainan Medical Journal
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