摘要
昆虫抗菌肽是一类具有免疫效应的小分子多肽,它具有热稳定、抗菌谱广、无免疫原性、作用机制独特等特性,是昆虫能够抵御自然界中有害微生物侵染的重要因素。近年来,随着有关抗菌肽作用机理及功能研究的深入,其在医药领域的研究越来越引起人们的关注。本文就昆虫抗菌肽的分类、生物功能、基因工程研究进展以及在医药领域的应用等作一综述。
Insect antimicrobial peptide is a kind of polypeptide which has the specific immunity from bacteria, fungi, virus and other pathogenic microorganisms. It has such characters as heat- durability, broad- spectrum antibiotic, no immunogen and specific mechanism, et al. Recently, insect antimicrobial peptide has been widely used in the prevention and treatment of infectious diseases with the background and application research on it. This paper briefly reviews its classification its biological functions, the development on genetic engineering and the application in medicine.
出处
《成都医学院学报》
CAS
2006年第1期66-70,76,共6页
Journal of Chengdu Medical College
关键词
昆虫
抗菌肽
基因工程
insect
antimicrobial peptides
genetic engineering
