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应用循环酶法对血液同型半胱氨酸的测定及临床应用分析 被引量:3

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摘要 目的对循环酶法测定血液同型半胱氨酸(HCY)的方法学进行初步评价并探讨其临床应用。方法通过循环酶法测定HCY的精密度及重复性,同时对71例健康体检者和20例脑梗死、20例高血压、20例冠心病患者血液中HCY进行测定。结果循环酶法测定HCY的批内平均变异系数为2.23%,批间平均变异系数为1.59%。71例正常人中,39例男性HCY为8.22~20.78μmol/L,32例女性HCY为4.74~14.8μmol/L。21例高血压患者中,男性14例,HCY为(23.76±11.58)μmol/L;女性7例,HCY为1(9.76±9.16)μmol/L。20例冠心病患者中,男性17例,HCY为(28.24±7.03)μmol/L;女性3例,HCY为(33.43±5.09)μmol/L。20例脑梗死患者中,男性10例,HCY为(19.32±10.11)μmol/L;女性10例,HCY为(18.00±3.16)μmol/L。结论循环酶法测定血液HCY具有较高的精密度,重复性好,试剂稳定,结果准确可靠,适合临床推广使用。HCY是心血管疾病特别是脑梗死、冠心病、高血压的危险指标,其浓度升高程度与疾病的危险性成正比。
出处 《福建医药杂志》 CAS 2007年第5期125-127,共3页 Fujian Medical Journal
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