摘要
目的探讨血清超敏C反应蛋白(Hs-CRP)与同型半胱氨酸(Hcy)的水平变化在冠状动脉粥样硬化性心脏病中的价值。方法选择稳定性心绞痛25例(A组)、不稳定性心绞痛41例(B组),分别记录入院时血清Hs-CRP、Hcy水平,并与患者冠脉造影结果血管腔面积作相关性分析。结果 A组患者平均血清Hs-CRP、Hcy明显低于B组,差异显著(P<0.05);两组患者平均血清Hs-CRP、Hcy两指标水平与血管腔面积呈正相关性(P<0.05)。结论冠心病患者血清Hs-CRP、Hcy在不稳定性心绞痛发病机制中可能起作用,两者升高提示可能与冠脉病变的程度有关。
Objective To study the clinical significance of changes in serum levels of high-sensitivity C-reactive protein（Hs-CRP） and homocysteine（Hcy） in patients with coronary heart disease.Methods Serum levels of Hs-CRP and Hcy were detected in 25 cases of stable angina（group A） and 41 cases of unstable angina（group B） at admission.All patients were examined with coronary angiography.Analysis on their correlation was made with the result of vessel area.Results The mean serum level of Hs-CRP in group A was lower than that of group B,their difference was statistically significant（P0.05）.The mean serum levels of Hs-CRP and Hcy had positive correlation with vessel area（P0.05）.Conclusion The serum levels of Hs-CRP and Hcy may play an important role in pathogenesis of unstable angina and they may be correlated with the degree of impaired coronary artery in patients.
出处
《临床和实验医学杂志》
2011年第24期1894-1895,共2页
Journal of Clinical and Experimental Medicine
