期刊文献+

血浆中胆红素和氧化型低密度脂蛋白水平与动脉粥样硬化的关系

暂未订购
导出
摘要 目的探讨血浆中低水平胆红素和高浓度氧化型低密度脂蛋白(Ox-LDL)对动脉粥样硬化(As)的影响。方法采用钒酸盐氧化法测血浆胆红素,用ELISA法测血浆中Ox-LDL。结果As患者血浆胆红素结果为(10·7±4·8)μmol/L,相比对照组(15·6±5·2)μmol/L,有显著差异(P<0·05),Ox-LDL结果As组为(625·3±257·2)U/L,显著高于对照组的(432·7±184·4)U/L(P<0·01)。结论血浆中低水平胆红素和高浓度Ox-LDL浓度与As有直接的关系。
作者 张斌 王爱华
出处 《中国厂矿医学》 2007年第5期533-533,共1页 Chinese Medicine of Factory and Mine
  • 相关文献

参考文献7

二级参考文献42

  • 1[1]Witztum J L, Steinberg D. Role of oxidized low density lipoprotein in atherogenesis[J]. J Clin Invest, 1991, 88(6)∶1785-1792.
  • 2[2]Hovoet P, Collen D. Oxidation of low density lipoproteins in the pathogenesis of atherosclerosis[J]. Atherosclerosis,1998,137(Suppl)∶33-38.
  • 3[3]Ehara S, Ueda M, Naruko T,et al.Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes[J]. Circulation, 2001;103(15)∶1955-1960.
  • 4[4]Smith C, Mitchinson M J, Aruoma O I,et al.Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions[J]. J Biochem,1992,286(3)∶901-905.
  • 5[5]Van der Wal A C, Becker A E, van der Loos C M,et al.Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology [J]. Circulation,1994,89(1)∶36-44.
  • 6[6]Hiltunen T P, Yl-Herttuala S. Expression of lipoprotein receptors in atherosclerotic lesions[J]. Atherosclerosis,1998,137(Suppl)∶81-88.
  • 7[7]Kaartinen M, Penttil A, Kovanen P T.Extracelluar mast cell granules carry apolipoprotein B-100-containing lipoproteins into phagocytes in human arterial initima. Functional coupling of exocytosis and phagocytosis in neighboring cells[J].Arterioscler Thromb Vasc Biol,1995,15(11)∶2047-2054.
  • 8[8]Yl-Herttuala S, Palinski W, Rosenfeld M E,et al. Evidence for the presence of modified low density lipoprotein in atherosclerotic lesions of rabbit and man[J].J Clin Invest,1989,84(4)∶1086-1095.
  • 9[9]Boyd H C, Gown A M, Wolfbauer G,et al.Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modiified LDL in atherosclerotic lesions from a Watanbe heritable hyperlipidemic rabbit[J]. Am J Pathol, 1989,135(5)∶815-825.
  • 10[10]Yl-Herttuala S, Butler S, Picard S,et al. Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL [J]. Arterioscler Thromb,1990,14(1)∶32-40.

共引文献216

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部