摘要
目的探讨慢性HBV感染者临床诊断的准确率。方法对187例慢性HBV感染者的临床、病理、免疫组化等资料进行分析。结果187例慢性HBV感染者临床诊断轻度者的准确率为92%,而中度者只有35%;95%的慢性HBV携带者的肝组织有炎症表现;血清HBeAg和HBV DNA阳性组和阴性组肝组织HBcAg阳性率比较差异有显著性。结论慢性乙型肝炎轻度患者临床诊断的准确率高,但在慢性HBV携带者,仅凭临床血生化检测往往要掩盖病情而延误治疗。
Objective To investigate the accuracy of clinical diagnosis of chronic hepatitis B as compared with pathological examination. Methods To analyze the clinical, pathological and immunohistochemical datas of 187 individuals with chronic HBV infection. Results The accuracy of chronic Hepatitis B of mild degree by clinical diagnosis was 92%, while it was only 35% in moderate degree; 95% of chronic hepatitis B carriers had mild inflammatory activity in liver biopsies; and patients with serum HBeAg and/or HBV DNA positive had a higher positivity of HBcAg in liver tissues as compared with those with HBeAg and/or HBV DNA negative. Conclusion The accuracy of chronic hepatitis B of mild degree by clinical diagnosis is high, while we suggest that the hepatitis B carriers should be followed by liver biopsy.
出处
《实用肝脏病杂志》
CAS
2007年第5期318-319,305,共3页
Journal of Practical Hepatology
