摘要
目的:探讨MSCT体积测量在评价原发性肝癌经肝动脉和门静脉双重栓塞治疗的价值。方法:经TACE联合经门静脉PCS双重治疗的手术不能切除的26例原发性肝癌患者为研究组,另选取30例单纯行TACE治疗的原发性巨块型肝癌患者为对照组,测量两组治疗前1d和治疗后2个月的肿块体积变化率和正常肝实质体积变化率。结果:26例研究组患者均顺利地完成了经TACE联合经门静脉PCS双重栓塞治疗,并获得了较好的疗效。研究组肿块的体积变化率为(-3.57±8.43)%,而对照组的体积变化率为(1.76±7.62)%,两组间差异有统计学意义(P<0.05)。研究组的正常肝实质体积变化率为(2.28±11.29)%,而对照组的正常肝实质体积变化率为(-10.35±14.61)%,两组间差异有统计学意义(P<0.01)。结论:MSCT体积测量可直观地评价原发性肝癌经肝动脉和门静脉双重栓塞的治疗效果。
Objective To evaluate the efficacy of double chemoembolization of primary hepatocellular carcinoma by transcatheter arterial cheomembolization and portal vein port catheter system with MSCT volumetric measurement. Methods In the test group, port catheter system was implanted in portal vein in 26 cases of irresectable primary hepatocellular carcinoma during operation. In all of the 26 cases, transcatheter arterial cheomembolization was performed. Two weeks later, chemoembolization of portal vein via port catheter system was also done. A total of 30 cases of hepatocellular carcinoma treated simply with transcatheter arterial cheomembolization were served as control group. The MSCT volumetric changing rate of the tumor and the normal hepatic parenchyma were measured before transcatheter arterial cheomembolization 1 day and 2 months after transcatheter arterial cheomembolization in all patients. Results There was a statistic difference in the MSCT volumetric changing rate of the tumor and the normal hepatic parenchyma between the two groups. The MSCT volumetric changing rate of the tumor in the test group was（-3.57±8.43）%, and （1.76 ± 7.62） % in control group. The MSCT volumetric changing rate of the normal hepatic parenchyma in test group and control group were （2. 28 ± 11. 29）%, and （-10. 35 ± 14. 61）% respectively. Conclusion MSCT volumetric measurement can directly reflect the effect of double chemoembolization of hepatocellular carcinoma by transcatheter arterial cheomembolization and portal vein port catheter system.
出处
《实用诊断与治疗杂志》
2007年第10期737-739,742,共4页
Journal of Practical Diagnosis and Therapy
基金
GE公司联合研发基金资助(2004E039)
关键词
肝肿瘤
栓塞
治疗性
肝动脉
门静脉
Liver neoplasm
embolization
therapeutic
hepatic artery
portal vein
