摘要
目的探讨乳腺癌浸润、转移过程中CD34表达及微血管密度的意义。方法采用免疫组织化学方法检测60例乳腺癌患者癌组织、癌旁2cm乳腺组织及距癌组织5cm以上正常乳腺组织中CD34的表达情况,检测3种组织中CD34标记的微血管密度。结果乳腺癌组织的微血管密度值(54.60±10.54)明显高于癌旁组织(33.05±7.70)和正常乳腺组织(25.40±5.71),差异均有统计学意义(P<0.01)。结论 CD34阳性表达与乳腺癌血管生成有一定相关性。
Objective To study the expression of CD34 in tumor infiltration and metastasis in breast cancer and the clinical significance. Methods The expression of CD34 was detected by using immunohistochernical method in the breast cancer tissues and adjacent tissues 2 cm from the margin of breast cancer tissues and normal tissues 5 em away from the margin of breast cancer tissues in 60 cases of breast cancer. The CD34 labeled rnicrovessel density was measured in breast cancer tissues. Results Microvessel density was 54. 60--10. 54 in breast cancer tissues, higher than that in adjacent tissues （33.05±7.70） and in normal tissues （25.40±5.71）, which showed significances among groups （P〈0.01）. Conclusion The expression level of CD34 is correlated with tumor angiogenesis.
出处
《中华实用诊断与治疗杂志》
2013年第3期260-261,共2页
Journal of Chinese Practical Diagnosis and Therapy
