摘要
目的:利用喷雾干燥法改善中药浸膏的吸湿性和流动性,最大限度地改善喷雾干燥的黏壁现象,为中药工业现代化提供合理的相对湿度环境及生产条件。方法:以正交试验法筛选最佳辅料配方以及最佳工艺条件,并考察浸膏干粉的吸湿性和流动性因素。结果:向溶液中加入3%微粉硅胶、7%β-环糊精,可以极大地降低浸膏粉的吸湿性。最佳工艺为浸膏比重1.10g.mL-1、进风温度170℃、雾化压力0.5Mpa、进料速度400mL.h-1;最佳处方的临界相对湿度为64%。结论:本研究结果可以改善传统干燥中药方法时间长、浸膏易吸湿等问题。
OBJECTIVE ： To improve hydroscopicity and fluidity of traditional Chinese drug extractum by spray drying and to improve affixes to the wall of the drier during drying for providing reasonable relative humidity of production. METHODS： The compounding of adjuvant and the technology were optimized by orthogonal experiment, and the hydroscopicity and fluidity of powdered extract were investigated, RESULTS： The hydroscopicity of traditional Chinese drug extractum can be greatly decreased by adding 3% gum arabic and 7% β-CD. The optimum technological conditions were as follows： extractum density of 1,10g·mL^-1, temperature of intake airflow of 170℃, atomization pressure of 0,5Mpa, and feed material speed of 400mL·h^-1 by orthogonal experiment. The critical relative humidity of the optimum formula was 64%. CONCLUTION： The problems of time consuming and moisture absorption of traditional Chinese drug extraetum existed in the traditional old technology can be improved in this new technology,
出处
《中国药房》
CAS
CSCD
北大核心
2007年第27期2114-2116,共3页
China Pharmacy
关键词
喷雾干燥
吸湿性
中药浸膏
改善
Spray drying
Hydroscopicity
Traditional Chinese drug extractum
Improvement
