摘要
目的观察高压氧(HBO)对鼻咽癌放疗后期各种并发症的治疗作用,并对其特异性疗效进行了综合评价。方法鼻咽癌患者40例,分为HBO组和对照组,两组均接受相同条件的放射治疗。HBO组20例,除常规处理外,同时给予HBO治疗。治疗压力为0.2 MPa(2.0 ATA)吸纯氧2次,每次40 min,每天1次,10 d为1个疗程,治疗8～12个疗程。对照组20例只给予常规处理。结果两组患者放疗后期并发症的发生率基本相似(P>0.05),但HBO组患者各种并发症的治愈率及缓解率均明显高于对照组(P<0.05)。结论HBO对鼻咽癌放疗后的各种并发症具有明显的治疗效果,可以减轻患者的痛苦,使其生活质量得到明显提高。
Objective To observe and evaluate the special clinical effectiveness of hyperbaric oxygenation therapy（HBOT） on the complications in nasopharyngeal carcinoma patients-who received radial radiotherapy. Methods Forty patients with nasopharyngeal carcinoma were randomly divided into HBO （ n = 20） and control （n =20） groups. In HBO group,the patients received 100% oxygen in a hyperbaric chamber at a pressure of O. 2 MPa （ 2.0 ATA） for 80 minutes per day （ 10 days as a course of therapy, and all the patients usually received 8 to 12 courses according to their disease status）. While in the control group, only routine therapy were received. Results The total incidence of radiation related complications after radiotherapy in two groups was basic similar （ P 〉 0. 05 ）. Compared with control group, healing and remission rate in HBO group were significant higher（ P 〈 0. 05 ）. Conclusions HBO is effective on radiotherapy-induced complications in patients with nasopharyngeal carcinoma, which may release painfulness and improve the life quality of them.
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
2007年第4期227-229,共3页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
关键词
鼻咽癌
放射性损伤
高压氧
Nasopharyngeal carcinoma
Radiation injury
Hyperbaric oxygenation
