摘要
将两类具有重要生物活性的结构单元β-氨基丁酸和糖分子结合在一个分子内,设计合成了8个新糖酯化合物.经元素分析和1H NMR确认了其结构.初步生物活性测定结果表明,该类化合物具有一定的诱导活性,且一些化合物的诱导活性比水杨酸的好.
The plant activators such as D,L-β-aminobutyric acids can induce systemically acquired resiatance in the treated plants against the pathogen infection. Saccharide carboxylate compounds are known for their physiological and pharmaceutical importance. In order to investigate the synergic effect of the glucose and β-aminobutyric acid , eight new glycosyl esters of β-aminobutyric acid were synthesized with the reaction of 3-N-benzyloxycarbonyl-β-aminobutyric acid with acetylated glycosyl bromide or di-O-isopropyllidene-glucose. The structures were confirmed via elemental analysis and ^1H NMR. Bioassay results indicate that several compounds show a better induced activity against pathogen infection than salicylic acid.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2007年第8期1512-1515,共4页
Chemical Journal of Chinese Universities
基金
国家自然科学基金重点项目(批准号:20432010)
国家自然科学基金(批准号:30270883)资助
