摘要
目的观察中药银黄滴眼液治疗单纯疱疹性角膜炎的临床疗效。方法采取随机、双盲、多中心、平行和阳性药物对照方法,将确诊的单纯疱疹性角膜炎患者223例分为观察组112例,对照组111例。观察组用银黄滴眼液,对照组用0.1%阿昔洛韦滴眼液,二者用药次数分别均为1次/2小时(白天用药),2滴/次,2周为1个疗程。结果银黄滴眼液能显著改善单纯疱疹性角膜炎(风热疫毒证)所导致的畏光流泪、目干涩痛、睫状充血和角膜病变等症状,愈显率达85.58%,并能有效提高裸眼视力和矫正视力。在用药7日的临床疗效及中医症候疗效的愈显率均优于对照组(P<0.05)。结论银黄滴眼液纯中药制剂比阿昔洛韦滴眼液起效快,不失为治疗单纯疱疹性角膜炎(风热疫毒证)的安全、有效药物。
OBJECTIVE To observe the curative effect of Yinhuang Eyedrop（银黄滴眼液）on treatment of HSK （syndrome of wind - heat and epidemic toxic）. METHODS With RCT design of randomization, double - blind, multi - center, parallel and positive- drug control, 223 patients with HSK（syndrome of wind- heat and epidemic toxic）were di- vided into two groups. One hundred and twelve patients as treatment group received Yinhuang Eyedrop and 111 patients as control group received 0.1% acycloviv eyedrop. Both groups received 2 drops of drug once every 2 hours in daytime, and the period of treatment was 2 weeks. RESULTS The symptoms of photophobia, tearing, ciliary congestion, kemtopathy and the sense of dry,acerbity or pain of eyes led by HSK were obviously improved,and the effective rate was 85.58 % in the treatment group, both the naked- eye visual acuity and rectified visual acuity advanced by using Yinhuang Eyedrop without special adverse drug reactions. However, the effective rate of treatment group was better than that of control group on the 7th medication day.There were statistical differences between the treatment group and control group （P 〈 0.05）. CONCLUSIONS Yinhuang Eyedrop has quicker effect than 0.1% acycloviv eyedrop. As a preparation of traditional Chinese medicine,Yinhuang eyedrop is effective and safe for HSK（syndrome of wind- heat and epidemic toxic）patients.
出处
《中国中医眼科杂志》
2007年第4期187-190,共4页
China Journal of Chinese Ophthalmology
关键词
单纯疱疹性角膜炎
银黄滴眼液
herpes simplex keratitis, HSK
Yinhuang Eyedrop（银黄滴眼液）
