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老年人呼吸道革兰阳性球菌对大环内酯类抗菌药物耐药监测研究 被引量：4

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摘要 将我院2002年1月至2006年6月间呼吸内科、干部病房及老年病科收治的老年下呼吸道感染患者的痰进行了针对性的病原菌分离培养，共检出优势菌1724株（1658株细菌和66株真菌），对其中的金黄色葡萄球菌和肺炎链球菌进行了大环内酯类抗菌药物耐药性监测和分析，并对肺炎链球菌由ermB和mefE基因介导的红霉素耐药进行调查。
作者 季海生 朱德全
机构地区 山东省临沂市人民医院临床检验中心
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2007年第7期818-819,共2页 Chinese Journal of Laboratory Medicine
关键词 大环内酯类 抗菌药物 下呼吸道 革兰阳性球菌 老年人 耐药监测 金黄色葡萄球菌 肺炎链球菌
分类号 R446.5 [医药卫生—诊断学]
  • 相关文献

参考文献5

  • 1CLSI. Performance Standards for Antimicrobial Susceptibility Testing; Sixteenth Informational Supplement. USA : CLSI, 2006, M100-S16:50.
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  • 5华春珍,尚世强,李建平,袁红.肺炎链球菌243株耐药性研究[J].中华检验医学杂志,2003,26(6):378-379. 被引量：20

二级参考文献12

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共引文献71

同被引文献23

  • 1肖观莲,陈佑明,黄敬,曾景文,彭若宇.老年人下呼吸道感染细菌谱及抗生素耐药性监测[J].中国现代医学杂志,2004,14(13):127-130. 被引量：9
  • 2张春,陆晓彤.儿童专科医院临床病原菌分布与抗菌药物耐药分析[J].中华医院感染学杂志,2006,16(4):434-437. 被引量：24
  • 3周英智,李艳,孙延霞,刘长庭.老年下呼吸道感染革兰阴性杆菌现状及耐药性监测[J].中华老年多器官疾病杂志,2006,5(2):108-110. 被引量：4
  • 4潘颖,付秀华,张志敏.下呼吸道感染病原菌分布及耐药监测[J].内蒙古医学院学报,2007,29(2):106-109. 被引量：3
  • 5Ken W,Crystal J,Barry G,et al. Use of clindamycin disks,to detect macrolide resistance mediated by ermB and mefE in Streptococcus pneumoniae isolates from adults and children [J]. J Clin Microbiol,2000,38:1731-1734.
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  • 7De Leener E, Martel A, Decostere A, et al. Distribution of the erm (B) gene, tetracycline resistance genes, and Tn1545 -- like transposons in macrolide- and lincosamide- resistant Enterococci from pigs and humans [ J ]. Microb Drug Resist, 2004,10:341 - 345.
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  • 9Nne - laure, Prunie, Selma L. Mutation of L4 ribosomal protein conferring unusual macrolide resistance in two independent clinical isolates of Staphylococcus aureUs [ J ]. Microbial Drug Resistance, 2005,11 ( 1 ) : 18 -21.
  • 10Catarina Milheirico. Update to the multiplex PCR strategy for assignment of mec element types in Staphylococcus aureus [ J]. Antimicrobial Agents and Chemotherapy,2007,51 (9) :3374 - 3377.

引证文献4

二级引证文献24

中华检验医学杂志
2007年 第7期

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