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儿科病房痰培养肺炎链球菌耐药性分析 被引量:7

Antibiotic resistance of 92 streptococcus pneumoniae isolated from children's sputum
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摘要 【目的】探讨儿科痰标本分离的肺炎链球菌对抗菌药物体外敏感性,为临床合理用药提供参考。【方法】对本院儿科2009年1月—2009年12月临床分离的92株肺炎链球菌的科室分布和药敏情况进行统计分析。【结果】儿童重症监护病房对阿奇霉素、克拉霉素、青霉素、红霉素、头孢曲松(脑膜炎)、亚胺培南、复方新诺明、四环素、利奈唑烷和万古霉素的耐药率分别为100.0%、100.0%、100.0%、95.8%、86.9.0%、65.2%、60.8%、48.0%、0%和0%;普通儿童内科病房耐药率分别为76.4%、76.9%、72.9%、81.2%、61.5.0%、42.5%、61.5%、65.2%、0%和0%。【结论】本院儿科肺炎链球菌对多种抗菌药物的耐药率均较高,建议临床应合理选择抗菌素。 【Objective】 To investigate the vitroantimicrobial susceptibility of Streptococcus pneumoniaeand to quide the rational use of drug clinically. 【Method】 We performed statistical analysis of the susceptibility of 62 strains of S.pneumoniae isolated in our hospital from January 2009 to December 2009. 【Results】 The resistance rates of Streptococcus pneumoniae strains were determined for the susceptibilities to antibiotics.The resistance rates of Azithromycin,Clarithromycin,Penicillin,Erythromycin,Ceftriaxone(meningitis),Imipenem,rimethoprim/Sulfa,Tetracycline,linezolid,vancomycin were 100.0%,100.0%,100.0%,95.8%,86.9.0%,65.2%,60.8%,48.0%,0%,and 0% respectively in pediatric intensive care(PICU);The resistance rates were 76.4%,76.9%,72.9%,81.2%,61.5.0%,42.5%,61.5%,65.2%,0% and 0% respectively in pediatric wards. 【Conclusion】 The resistance rates of streptococcus pneumoniae to several kinds of antibiotics are relatively high,therefore clinical use antibiotics should be reasonable.
出处 《中国儿童保健杂志》 CAS 2010年第8期691-694,共4页 Chinese Journal of Child Health Care
关键词 肺炎链球菌 细菌耐药性 抗生素 儿科 streptococcus pneumonia drug resistance antibiotic pediatric
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