摘要
微晶纤维素与新速效感冒片中的扑热息痛混合研磨,能提高该药的溶出度。溶出值与研磨时间、微品纤维素用量有线性关系。在一定范围内研磨时间越长,溶出效果越好,微晶纤维用量越大,溶出度越好;内加法比外加法效果好。
In order to increase the liberation of the drug microcrystalline cellulose was mixed with ac- etaminophen of the new speedly—effective Ganmao tablets in an attempt to increase its libera- tion.There was linear relationship between the liberation and the time of grind or the dosage of microcrystalline cellulose.In a certain range,the longer the time of grind and better the liberation of thd drug.
关键词
微晶纤维素
扑热息痛
溶出度
片剂
药理
microcrystalline cellulosa
acetaminophen
liberation
mixed grind
