摘要
目的:研究静脉腔作为管状移植体在面神经再生过程中所起的作用。方法：雄性SD大鼠12只，随机分静脉套接组、神经原位移植组、对照组。面神经干移植术后3个月，光镜下观察神经束的分布与变化；网格测微尺下测量移植体相应部位面神经干的神经束面积、轴突数、轴突密度。结果：静脉腔内神经由多束组成，神经移植体内以一大束为主、众小束排列其周围；正常面神经干为一单束；神经原位移植组的神经束面积、轴突数均显著大于其他两组，但3组的轴突密度无显著差异。结论：静脉管腔内的微环境有利于再生面神经轴突生长。
To study the role of vein tubulation in the facial nerve regeneration. Methods:Twelve male adult SD rats were divided randomly into vein tubulation group,nerve graft group and normalcontrol group- The facial nerve trunks were cut and grafted’ Three months p0stoperation, the distributionand variation of the fascicles were observed under light microscope. Fascicular area,axon number and axondensity were gauged and caculated. Results:Within the vein chamber, the regenerating nerve consisted ofmany fascicles. In the nerve graft, there was a major fascicle surrounded by many small fascicles. Thenormal facial nerve trunk had only one fascicle. Among 3 groups, the fascicular area and axon number ofthe nerve graft were largest, but the axon density had no significant difference. Conclusion: The micr0en-vironment in vein chamber may be beneficial to growth of regenerating axons.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
1997年第1期35-37,共3页
Academic Journal of Second Military Medical University
基金
全军"八五"规划青年科研基金!91D044-0295
