2Hirata Y,Yanai A,Shibata W,et al.Functional variability of cagA gene in Japanese isolates of Helicobacter pylori[J].Gene,2004.343(1):165-72.
3Azuma T,Yamazaki S,Yamakawa A,et al.,Association between diversity in the Src homology 2 domain--containing tyrosine phosphatase binding site of Helicobacter pylori CagA protein and gastric atrophy and cancer[J].J Infect Dis,2004,189 (5):820-827.
4Argent RH,Kidd M,Owen RJ,et al.,Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori[J].Gastroenterology,2004,127 (2):514-23.
5Yamaoka Y,Kodama T,Kashima K,et al.Variants of the 3 ' region of the cagA gene in Helicobacter pylori isolates from patients with different H.pylori-associated diseases[J].J Clin Microbiol,1998,36 (8):2258 -2263.
6Higashi H,Yokoyama K,Fujii Y,et al.EPIYA motif is a membranetargeting signal of Helicobacter pylori virulence factor CagA in mammalian cells[J].J Biol Chem,2005,280(24):23130-23137.
8Odenbreit S,Puls J,Sedlmaier B,et al.,Translocation of Helicobacter pylori CagA into gastric epithelial cells by type Ⅳ secretion[J].Science,2000,287 (5457):1497-1500.
9Higashi H,Tsutsumi R,Muto S,et al.,SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein[J].Science,2002,295(5555):683-668.
10Higashi H,Tsutsumi R,Fujita A,et al.Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites[J].Proc Natl Acad Sci U S A,2002,99(22):14428-14433.
2EL-OMAR GM. The importance of interleukin 1β in helicobacter pylori associated disease [J]. Gut, 2001, 48(6):743-747.
3CRAANEN ME, BLOK P, DEKKER W, et al. Subtypes of intestinal metaplasia and Helicobacter pylori[J]. Gut, 1992, 33(5) :597-600.
4TAKASHIMA M, FURUTA T, HANAI H, et al. Effects of Helicobacter pylori infection on gastric acid secretion and serum gastrin levels in Mongolian gerbils [J]. Gut, 2001, 48(6):765-773.