2Hirata Y, Yanai A, Shibata W, et al. Functional variability of cagA gene in Japanese isolates of Helicobacter pylori. Gene, 2004,343(1): 165-172.
3Azuma T, Yamazaki S, Yamakawa A, et al. Association between diversity in the Src homology 2 domain-containing tyrosine phosphatase binding site of Helicobacter pylori CagA protein and gastric atrophy and cancer. J Infect Dis, 2004,189(5) :820-827.
4Argent RH, Kidd M, Owen RJ, et al. Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori. Gastroenterelogy, 2004,127(2) :514-523.
5Yamaoka y, Kodama T, Kashima K, et al. Variants of the 3' region of the cagA gene in Helicobacter pylori isolates from patients with different H. pylori-associated diseases. J Clin Microbiol, 1998,36(8):2258-2263.
6Higashi H, Yokoyama K, Fujii Y, et al. EPIYA motif is a membrane-targeting signal of Helicobacter pylori virulence factor CagA in mammalian cells. J Biol Chem, 2005,280(24):23130-23137.
7Kim SY, Lee YC, Kint HK, et al. Helicohacter pylori CagA transfection of gastric epithelial cells induees interleukin-8. Cell Microbiol, 2006,8(1):97-106.
8Odenbreit S, Puls J, Scdlmaier B, et al. Translocation of Helicobacter pylori CagA into gastric epithelial cells by type Ⅳ secretion. Science, 2000,287(5457) : 1497-500.
9Higashi H, Tsutsumi H, Muto S, et al. SHP-2 tyrosine phosphatase as an intracellular target of Hclicobacter pylori CagA protein. Science, 2002,295(5555) :683-686.
10Higashi H, Tsutsumi R, Fujita A, et al. Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites. Proc Natl Acad Sci U S A, 2002,99(22):14428-14433.
