摘要
为研究人晶体后囊混浊行Ｎｄ：ＹＡＧ激光切开术对角膜内皮细胞的影响，用Ｎｄ：ＹＡＧ激光治疗３３例（３３只眼）后囊混浊切开，在激光前与激光后７天检测内皮细胞。结果①激光前角膜内皮细胞平均密度为２４０１个／ｍｍ２，激光后７天内皮细胞密度为２３０１个／ｍｍ２，内皮细胞丢失率为４．３８％，六边形细胞丢失率６．５８％。②激光后与激光前的内皮细胞密度及六边形细胞百分数均有统计学显著性差异（分别为ｔ＝３．６１，ｐ＜０．０５；ｔ＝４．２８，ｐ＜０．０１）。③切开后囊所用激光总能量与内皮细胞丢失无相关性，而单次激光能量则与其有统计学上相关性（ｒ＝０．４３６４，ｐ＜０．０５）。结论Ｎｄ：ＹＡＧ激光行后囊混浊切开时，其对角膜内皮细胞有一定的影响，为减少对内皮细胞的损害，单次低量，多次的切开后囊的激光使用为最佳方法。
Objective The effect of capsulotomy using Nd:YAG laser on corneal endothelial cells was studied.Methods Corneal endothelial cell loss was detected in 33 human eyes with posteior capsular opacity before and after seven days of capsulotomy using Nd:YAG Laser.Results(1)The mean preoperative endothelial cell density was 2401/mm 2,while the mean postoperative was 2301/mm 2.The percentage of endothelial cell loss was 4 38% and the percentage of loss of hexagonal cells was 6 58%;(2)There was significant correlation between pre and postoperative endothelial cell densitses and the percentages of hexagonal cells(t=3 61.p<0 05;t=4 28.p<0.01).(3)There was no significant correlation between mean total laser energy and endothelial cell loss in posterior capsulotomy.but the pulse energy per single burst was statistically signigicant(r=0 496,p<0 05).Conclusion Nd:YAG laser has some injurious effect on corneal endothelial cells by applying it for posterior capsulotomy.In order to reduce this damage,the best management of Nd:YAG laser is using low pulse energy for multiple times.
出处
《中国实用眼科杂志》
CSCD
1997年第3期161-163,共3页
Chinese Journal of Practical Ophthalmology
关键词
后囊混浊
角膜内皮细胞
激光疗法
posterior capsular opacification Nd:YAG laser energy corneal endothelial cell
