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自身免疫病的生物学治疗进展 被引量:2

Advancement of biological therapy for autoimmune diseases
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摘要 临床工作中,自身免疫病的治疗极具挑战性,传统上采用的糖皮质激素和免疫抑制剂等化学药品治疗虽然有效,但长期使用都不可避免的带来很多毒副作用。近10余年来,基于该病发病机制中不同环节的特异性生物学治疗成为热点,它们的应用使治疗过程能够终止自身免疫反应的破坏作用而又不伤害正常的免疫防御系统成为可能。 Treating autoimmune diseases (AID) is a challenge for physicians. Traditionally, we use cortisone or other immune inhibitors to treat AID although we know that these kinds of drugs can cause some severe toxic action on patients if used longer. For over ten years, the biological therapy for AID, which specially targets to the pathogenesis of AID, has long been engaged in the study. These new drugs can protect the normal immune system while stopping undesirable immune reaction to the target organ.
作者 朱本章 蒲丹
出处 《西安交通大学学报(医学版)》 CAS CSCD 北大核心 2007年第3期233-236,251,共5页 Journal of Xi’an Jiaotong University(Medical Sciences)
基金 国家自然科学基金资助项目(No.30370678)
关键词 自身免疫病 传统治疗 生物学治疗 autoimmune disease (AID) traditional therapy biological therapy
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