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肝硬化患者血清IGF-Ⅱ水平与HA、PⅢP的关系 被引量:2

Relationship Between Serum Levels of IGF-Ⅱ and HA,PⅢP in Patients with Hepatic Cirrhosis
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摘要 目的:探讨了肝硬化患者血清IGF-Ⅱ水平与HA、PⅢP的关系。方法:应用放射免疫分析对65例肝硬化患者进行了血清IGF-Ⅱ和HA、PⅢP含量检测,并以30名正常健康人作比较。结果:肝硬化患者血清IGF-Ⅱ水平非常显著地高于正常人组(P<0.01),且与HA、PⅢP呈明显正相关。结论:检测肝硬化患者血清中IGF-Ⅱ水平对观察病情和预后判断均具有重要的临床价值。 Objective To investigate the clinical significance of changes of serum IGF - Ⅱ, HA and P Ⅲ P levels in patients with hepatic cirrhosis. Methods Serum IGF - Ⅱ , HA and P Ⅲ P levels were measured with RIA in 65 patients with hepatic cirrhosis and 30 controls. Results Serum IGF - Ⅱ levels were significantly higher than those in controls (P 〈 0.01 ), and were significantly positively correlated to the serum levels of HA, PⅢP. Conclusion Determination of serum IGF - Ⅱ levels in patients with hepatic cirrhosis is of help for assessment of the severity of diseases as well as outcome prediction.
作者 郑丹
出处 《放射免疫学杂志》 CAS 2007年第3期233-234,共2页 Journal of Radioimmanology
关键词 肝硬化 胰岛素样生长因子-Ⅱ 透明质酸 胶原蛋白-Ⅲ hepatic cirrhosis, IGF- Ⅱ, hyaluronic acid (HA), procolagen type - Ⅲ(PⅢP)
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