摘要
糖原组学是研究糖类的结构及其功能特性特别是糖类发挥作用的生物学机制的一门新型学科,将成为生命科学研究中的新热点。多糖及其缀合物在生命活动过程中贮存着各种生物信息,在细胞内外之间传递各种物质。目前,β-葡聚糖的研究是该领域研究最为广泛的糖类,其中研究最早的是香菇多糖,因为它具有免疫活性和抗肿瘤作用;作者对多糖的生物学地位以及β-葡聚糖的结构及其与生物学功能的关系的研究进展作一简述。葡聚糖的生物活性与其分子量、溶解度、黏度、支化度、链构象及结晶度有关,β-葡聚糖具有多种不同的构象,一重和三重螺旋是其存在的主要高级结构形式。
Glycomics, a new subject, is specialized on research of structure and functional features of carbohydrates, especially the biological mode of actions by carbohydrates; therefore glycomics comes to be one of the hot topics of life science research. Polysaccharides and their derivers play a role of reserving various biological information during the whole life time and activities, and transferring substances intra and extra-cellular as well as between cells. At present, β-glucan is one of the most popular research subjects （i. e. carbohydrate research） in the area, among which the earliest sugar studied is Lentinan because of its immunoactivities and anticancer activities The article is a review on biological status of posaccharides, structure of β-glucans, and the relationship between the structure of β-glucans and their biological functions. It is described in the article that biological activities of a glucan relate to the molar weight, solubility, branch chain, structure and crystal of the sugar. It was found that β-glucan has many different structures but one- and three-helixes are main forms of senior structures of β-glucan.
出处
《中国畜牧兽医》
CAS
2007年第5期152-155,共4页
China Animal Husbandry & Veterinary Medicine
关键词
Β-葡聚糖
生物学地位
构效关系
glucans
biological status
structure and function relationship
