摘要
目的探索对于康复期的精神分裂症患者药物治疗合并小组认知行为治疗是否优于单纯使用药物治疗。方法对总病程少于五年的56名门诊恢复期精神分裂症患者,随机分配到药物治疗结合认知心理治疗的试验组(n=28)及单纯使用药物的对照组(n=28),试验组进行5次小组认知行为治疗。在治疗前、治疗开始后6个月及9个月进行阳性和阴性症状量表、大体评定量表及Montgomery-Asberg抑郁量表的评估。结果试验组在6月的评定中PANSS总分(P<0.01)、阳性症状得分(P<0.01)、一般精神病理得分(P<0.01)、MADRS得分(P<0.01)的减少量及大体评定得分(P<0.01)得增加值与对照组比较有统计学意义上的差异。在9月的评定中阴性症状量表的得分与对照组相比也出现了统计学上的差异。结论合并小组认知行为治疗的试验组,在精神病症状,抑郁情绪及大体评定上的改善要优于单纯药物组。小组认知行为治疗可以作为一种精神分裂症康复期病人很有前景的辅助治疗方法。
Objective： To study whether patients with a CCMD- Ⅲ diagnosis of schizophrenia after acute episode would improve better with the addition of group cognitive - behavioural therapy （GCBT） than medication only. Methods： 56 patients with whole course less than 5 years were divided randomly to either medication plus group cognitive - behavioural therapy （ n = 28） or medication only （ n = 28）. Group cognitive - behavioural therapy was conducted in 5 sessions. The Positive and Negative Syndrome Scale （PANSS）, Global Assessment Scale and Montgomery - Asberg Depression Scale were done at pretreatment, 6 - month and 9 - month by raters. Results： At 6 - month significant reduction was observed for PANSS （ P 〈 0.01 ）, PANSS - Positive （ P 〈 0.01 ）, PANSS - General （ P 〈 0.01 ）, Montgomery - Asberg Depression Scale （ P 〈 0.01 ） and increment for Global Assessment Scale （ P 〈 0.01 ） for patients treated in GCBT plus medication than medication only. At 9 - month significant reduction were observed for PANSS - Negative for patients treated in GCBT plus medication than medication only. Conclusion： Group cognitivebehavioural therapy could improve psychosis symptoms, depression symptoms and Global Assessment scores. So it was a promising adjunctive treatment for patients with schizophrenia after acute episode.
出处
《华西医学》
CAS
2007年第2期236-237,共2页
West China Medical Journal
基金
"十五"国家科技攻关计划临床医学项目(2004BA720A22)
关键词
精神分裂症
认知行为治疗
精神病
Schizophrenia
cognitive behavioural therapy
psychosis
