摘要
目的了解枣庄市诱发儿童支气管哮喘常见吸入性变应原的构成情况，为本病环境干预提供依据。方法根据枣庄市支气管哮喘流行病学调查结果，对0～14岁哮喘和非哮喘儿童分别随机抽取31例作为观察组和对照组，两组均进行吸入性变应原皮肤点刺试验检查。结果吸入性变应原皮肤点刺试验观察组阳性率为83．87％（26／31），对照组为38．71％（12／31），观察组高于对照组，两组比较差异有统计学意义（x^2=13．33，OR=8．23，95％CI：2．48～27．32，P〈0．001）。观察组在10种常见吸入性变应原中室内尘土和螨的阳性反应率最高，分别为58．06％（18／31）和48．39％（15／31）。结论枣庄市诱发儿童哮喘的主要吸入性变应原是室内尘土和螨。
Objective To investigate the proportion of common inhalational allergens which could induce childhood bronchial asthma in Zaozhuang area, and to provide the scientific basis for environmental intervention. Methods According to the epidemiologic data of bronchial asthma in Zaozhuang area, 31 asthma and 31 non - asthma children aged 0 - 14 years were randomly selected and divided into the study group and control group. The skin spot pricking were taked with 10 inhaltational allergens in the two groups. Results The overall response rate was 83.87% （26/31） in the study group, and 38.71% （12/31） in the control group.There was significant difference in response rate between two groups （x^2 = 13.33, OR = 8.23, 95%CI： 2.48- 27.32, P 〈0.001）. The rates of positive reaction to house dirt （58.06%） and dermatophagoides （48.39%） were the highest in 10 kinds of inhalational allergens in the study group. Conclusion The inhalational allergens that cause childhood bronchial asthma in Zaozhuang area are mainly house dirt and dermatophagoides.
出处
《中国自然医学杂志》
CAS
2007年第2期99-101,共3页
Chinese Journal of Natural Medicine
关键词
哮喘
吸入性变应原
儿童
Asthma
Inhalational allergens
Children
