摘要
目的观察拉西地平治疗原发性高血压的疗效、不良反应及对患者生化代谢的影响。方法60例原发性高血压患者,每次服用拉西地平4.0-5.0 mg连续6个月,观察动态血压、心肌肥厚状况、不良反应及生化指标。结果60例高血压患者均坚持服用6个月以上,显效45例,有效11例,总有效率93.3%(56/60);35例伴有心肌肥厚的患者,超声心动图指标有明显改善(P<0.05);不良反应主要为头晕、面部潮红和下肢轻度肿胀,发生率11.7%(7/60),均可耐受;治疗前后空腹血糖、血脂、肾功能及血电解质无显著变化(P>0.05)。结论拉西地平治疗原发性高血压,效果确切,不良反应少,且对逆转心肌肥厚有一定作用。
Objective To observe the curative effect and side effect of lacidinpine in treating primary hypertension, the affection on metabolism of biochemistry. Methods 60 cases of such patient were treated with lacidinpine 4 - 5 nag for 6 months. The ambulatory Bp, myocardial, hypertorphy side effect and biochemi were observed. Results There were excellent in 45 cases, good in 11 eases with total effective rate of 93.3 %. 35 cases who had hypertrophy were improved. The side effects were mainly dizziness, redface and slight edema of lower limbs with 11.7 % and those were endurance. There were no abnormal change of biochemistry. Conclusion The lacidipine might treat primary hypertension effective with less side effect and might imorove the reverse of myocardiac hypertrophy.
出处
《黑龙江医学》
2007年第4期277-278,共2页
Heilongjiang Medical Journal
关键词
拉西地平
高血压
原发性
疗效
肥大
左心室
Lacidipine
Hypertension
Primary
Curative effect
Hypertrophy
