摘要
目的:研究板蓝根提取液抗甲1型流感病毒鼠肺适应株的作用及其对机体免疫力的影响。方法:用鸡胚培养法观察板蓝根提取液灭活甲1型流感病毒鼠肺适应株;以病毒滴鼻感染小鼠,建立病毒感染小鼠的模型,观察肺指数、病毒致小鼠死亡率,无菌进行脾T、B淋巴细胞增殖实验。结果:(1)鸡胚实验显示,板蓝根提取液能明显灭活病毒。(2)动物实验表明,经过板蓝根提取液治疗的小鼠死亡率明显降低,肺脏病变减轻,免疫细胞增多。结论:板蓝根提取液具有一定的抗甲1型流感病毒鼠肺适应株和增强机体免疫力的作用。
Objective： To study the effects of extractive of Radix Isatidis on influenza virus FM1 and its effects on immunity of body. Methods： The antiviral effects of extractive of Radix Isatidis on influenza virus FM1 were observed in chick-embryo culture and ICR mice. The mice were infected with influenza virus from nose. The lung index and death rate of mice infected by influenza virus was observed. The spleen T and B lymphocyte transformation experiment was carried out in aseptic environment. Results： （1） The extractive of Radix Isatidis showed significant inactivation of the influenza virus FM1 on chick-embryo culture. （2） The death rate of ICR mice was reduced, the pathological change of lung was improved and the immunological cells were irritated after using the extractive of Radix Isatidis. Conclusion： Extractive of Radix Isatidis has antiviral effects on influenza virus FM 1 and increases the immunity of body.
出处
《天津医科大学学报》
2007年第1期19-22,共4页
Journal of Tianjin Medical University
