摘要
本实验观察了大鼠黑质网状部（ＳＮＲ）微量注射ＧＡＢＡ０．２μｌ（１Ｍ）对，黑质Ⅰ、Ⅱ型神经元单位放电的影响。结果如下：（１）在记录的２５个Ⅰ型神经元中，有１７个单位（６８．００％）自发放电频率降低范围８８．４１％－１００．００％，平均降低９６．６２％±４．０１％。（２）在记录的３６个Ⅱ型神经元中，有２７个单位（７９．４１％）自发放电频率降低范围４３．５６％－９９．３５％，平均降低７８．６９％±１０．１３％。结果表明，黑质网状部微量注射ＧＡＢＡ能使大多数黑质Ⅰ、Ⅱ型神经元产生明显的抑制作用。
The effects of microinjection of GABA(0.2μl.1M)into the substantia nigra reticulata(SNR) on the unit discharges of Type Ⅰ and Type Ⅱ neurons in the substantia nigra (SN)of rats were observed The results showed that[1]the spontaneous discharge rate of 17/25 Type Ⅱ neurons were decreased by 88.41%-100.00%(96.62%±4.01%,x±sx) after SNR injection of GABA[2]the spontaneous discharge rate of 27/36 Type Ⅱ neurons were also decreased by 43.56%-99.35%(78.69%±10.13%). The results indicated that SNR injection of GABA can inhibit both Type Ⅰ and Type Ⅱ neurons in SNR
出处
《锦州医学院学报》
1996年第5期1-4,共4页
Journal of Jinzhou Medical College
关键词
黑质
GABA
神经元
单位放电
substantia nigra
GABA
Type Ⅱ neurons
Type Ⅱneurons
unit discharge
