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血管升压素在脓毒性休克中的研究进展 被引量：5

Study on vasopressin during septic shock
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摘要 血管升压素是维持心血管功能稳定的重要内源性物质。但脓毒性休克时,其在体内却相对不足,给予外源性血管升压素可引起显著的血管升压效应。目前,脓毒性休克时机体血管升压素缺乏以及机体对其敏感性增高的具体机制尚不清楚。目前研究认为,血管升压素受体改变、收缩和舒张血管因素、自主神经系统和下丘脑-垂体-肾上腺轴均参与了血管升压素高敏感性机制的调节。 Vasopressin is an important endogenous hormone for cardiovascular homeostasis. Vasopressin is relatively deficient during septic shock. In the circumstances, exogenous vasopressin can induce obvious vasopressor effects. Now the mechanisms of vasopressin deficiency and hypersensitivity in septic shock are unclear. The potential mechanisms underlying vasopressin hypersensitivity include changes of vasopressin receptors, interacting with other vasoconstrietion/vasodilatation factors, autonomic nervous svstem and the hvoothalamie -oituitarv -adrenal axis.
作者 薄禄龙 邓小明
机构地区 解放军第二军医大学附属长海医院麻醉科
出处 《中国急救医学》 CAS CSCD 北大核心 2007年第3期249-251,共3页 Chinese Journal of Critical Care Medicine
关键词 血管升压素 脓毒症 脓毒性休克 Vasopressin Sepsis Septic shock
分类号 R459.7 [医药卫生—急诊医学]
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参考文献24

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二级参考文献10

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共引文献36

同被引文献35

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引证文献5

二级引证文献18

中国急救医学
2007年 第3期

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