摘要
箬叶多糖对小鼠实验性四氯化碳致肝损伤的作用陈春英丁玉强ＥｌｈａｇＡＥＬＭＡＨＡＤＩ１周井炎李焰徐辉碧（华中理工大学化学系，武汉４３００７４；１ＥｌｇａｚｉｒａＵｎｉｖｅｒｓｉｔｙ，ＷａｄｅｎｉＰＯＢｏｘ４２，Ｓｕｄａｎ）箬叶是禾本科植物箬竹（Ｉｎｄｏ...
Indocalamus tessellatus polysac charides (ITPS) were extracted from the dry bamboo leaves of Indocalamus tessellatus with 85% ethanol (FE), 95 ℃ water (FⅠ), 5% NaOH (FⅢ 1, FⅢ 2) and 20% NaOH (FⅣ). Effects of these ITPS on liver of 6% CCl 4 oil solution 10 mL·kg -1 treated mice were studied. Various fractions of ITPS 80 mg·kg -1 ip respectively, once a day for 7 d significantly inhibited the MDA formation in hepatic mitochodrion and microsome, decreased the microviscosity of hepatic mitochodrial membrane and increased the SOD activity of liver. These results suggest that ITPS are protective against CCl 4 induced liver damage.
出处
《中国药理学与毒理学杂志》
CAS
CSCD
北大核心
1996年第3期237-238,共2页
Chinese Journal of Pharmacology and Toxicology
关键词
箬叶多糖
四氯化碳
肝损伤
中草药
Indocalamus tessellatus polysaccharides
carbon tetrachloride
free radicals
liver
