摘要
目的研究酒精性肝病(ALD)的临床特征,旨以早期诊断及治疗。方法样本为45例ALD,包括酒精性脂肪肝、酒精性肝炎及酒精性肝硬化。研究与饮酒相关的社会资料、病史、临床表现、血常规、肝功、血脂及血糖以及治疗后恢复情况,并设对照组比较。结果ALD组平均43·4±9·3岁;汉族、工人、持续饮白酒者居多;饮酒年限17·7±7·6年、折合乙醇量为164·1±71·7g/日。与对照组比较食少、消瘦、出血、肝大者明显增多;血清GGT、CHE、TP、ALB、TRIG含量以及PT明显异常;AST/ALT及GGT/ALP明显增高(P=0·000);经戒酒及治疗后恢复明显。结论本组ALD为北方、男性、饮酒量大的特点。与病毒性肝病比较,临床及实验室有一定的特征性表现。
Objective To investgate the clinical feature of ALD. Methods Samples are 45 patients with ALD,ineluding alcohlic fatty liver, alcoholic hepatitis and alcoholic cirrhosis. Society data related to alcohol intake was investgated, which include medical record, clinical manifestation, general examination of bloold, liver function, blood-fat, serum glucose and recovery status after treatment. At the same time, control group of non-alcohol consumers was set up. Resolts Patients of ALl） group were mainly characteristic of Han people,worker,drinking distillate spirit eontinuely. Mean age is 43.3 ± 9.3, induction time of alcohol was 17.7 ± 7.6 years,and quantity of alcohol intaked is 164.1 ± 71.7 each day,in ALD group. Characterities of ALD group were anorexia, maransis, hemorrhage, hepatauxe. Content of GGT, CHE, TP, ALB, TRIG and PT in blood serum were abnormal obviously. Quantities of GGT/ALP and AST/SLT increased obviously compared with control. With abstinence and treatment, patients recovered markedly. Conclusion ALD group was characteristic of north living male and large amouht of alcohol intake. Its is different in clinical appearance and lab index compared with viral hepatitis in clinic and laboratory.
出处
《胃肠病学和肝病学杂志》
CAS
2006年第6期587-589,共3页
Chinese Journal of Gastroenterology and Hepatology
关键词
饮酒
酒精性肝病
临床特征
肝功能
Alcohol intake
Alcoholic liver disease
Clinical feature
Liver function
