摘要
目的:探索普通成年男性血清生殖激素水平与精液量以及精子密度的关系。方法:资料来源于对5个研究现场(河北省石家庄市、山西省太原市、贵州省贵阳市、浙江省杭州市及山东省青岛市)的普通成年男性的横断面调查。同时收集研究对象的血样和精液样本,分析黄体生成素(LH)、卵泡刺激素(FSH)、睾酮(T)以及雌二醇(E2)与精液量、精子密度之间的关系。结果:共招收研究对象978名,通过相关分析及方差分析表明,高水平T对象的精子密度较低;高水平E2对象精液量较少。Logistic回归分析发现,高水平T发生低精子密度的危险性大,低水平的LH发生低精子密度的危险性小。结论:普通成年男性血清中生殖激素水平与精液数量指标有关,但表现出的某些关联性用已知的下丘脑-垂体-睾丸轴调节机制尚无法完全解释。
Objective: To investigate the relationships between serum reproductive hormones and sperm density and semen volume in ordinary adult men. Methods: This study was a cross-sectional epidemiological survey, combined with laboratory measures of hormonal profiles (FSH, LH, T, and E2) and semen. The data came from the ordinary volunteers in 5 selected cities of China (Shi Jiazhuang, Tai Yuan, Hang Zhou and Qing Dao). Results: A total of 978 eligible subjects were recruited, the liner correlation analysis and variance analysis showed that sperm density was significantly lower in high T group compared with low groups, and semen volume in high E2 group was less than low groups. The logistic regression analysis showed that high T group had a higher risk for low semen density and low FSH had a lower risk. Conclusion: Semen measures in ordinary adult men were related to serum reproductive hormones, but well-known hypothalamic- pituitary-testicular axis could not fully explain their relationships.
出处
《生殖与避孕》
CAS
CSCD
北大核心
2006年第11期679-683,共5页
Reproduction and Contraception
基金
国家人口和计生委资助项目
项目编号为9902
关键词
生殖激素
精子密度
精液量
reproduction hormone
sperm density
semen volume