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还原型谷胱甘肽治疗抗结核药物性肝损 被引量:3

Study on effect of GSH in treating liver-damaged patients who had used anti-tuberculosis drugs
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摘要 目的了解GSH治疗抗结核药物性肝损的疗效。方法肺结核患者在抗结核治疗过程中出现抗结核药物性肝损,且达到停药标准时,治疗组每天用1.8gGSH加入生理盐水250ml中静滴,对照组则以维生素C2g替代GSH,两组疗程均25~30d,疗程满后再次复查肝功能。结果实验组和对照组治疗有效率分别为92%56%(P〈0.05)。结论GSH对治疗抗结核药物性肝损有效。 Objective To observe the effect on the tuberculosis patients using anti-tuberculosis drugs liver lesion. Method The treatment group was given at a dose of 1.8 g/d for 25 - 30 days, dissolved with 0. 9% conccntrtion N. S 500 ml by intravenous drip and control group was given vitamin C at a dose of 2.0 g/d instead at the same time take the Norman liver function as effective in therapy after retest the liver function. Compare the effective rate and significant difference between the two group usingx2. Results The effective rate of the treatment group (92%) as higher than the control group(56% ) (P 〈0. 05 ) , there were significant difference between them. Conclusion It is effective in therapy of anti-tuberculosis drugs liver lesion.
作者 冯蝶仪 刘琨
机构地区 广州市胸科医院
出处 《临床肺科杂志》 2006年第6期743-744,共2页 Journal of Clinical Pulmonary Medicine
关键词 还原型谷胱甘肽 结核 药物 肝损 tuberculosis drug liver lesion
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