摘要
目的研究直肠癌淋巴结转移状态对区域缓释化疗(regionalextendedreleasechemothera-py,RERC)和淋巴化疗(lymphaticchemotherapy,LC)药物聚集浓度的影响。方法分别采取RERC组和LC组直肠癌肠上、肠旁淋巴结、肠系膜血管旁和肠系膜血管根部淋巴结,进行病理学及淋巴结内药物浓度分析。结果LC组和RERC组直肠癌3站肿瘤转移阳性与阴性淋巴结内药物浓度进行比较差异无统计学意义(P>0.05)。结论直肠癌淋巴结转移状态对RERC和LC淋巴结内药物浓度聚集无明显影响。
Objective To study the influnence of tumor metastasis status of rectal cancer lymph nodes in drug concentration for lymphatic chemotherapy （LC） and regional extended release chemotherapy （RERC）. Methods The lymph nodes in LC group and RERC group were collected from rectal cancer, side colon, side and root site of mesentery blood vessel for pathological observation and drug concentration analysis. Results There is no statistical difference on drug concentration for LC or RERC in lymph nodes in both groups with or without tumor metastasis （ P〉0.05）. Conclusion Tumor metastasis status of rectal cancer lymph nodes exerts insignificant effect on drug concentration for LC and RERC.
出处
《消化外科》
CSCD
2006年第5期308-310,共3页
Journal of Digestive Surgery
基金
上海市科委重点攻关项目(No.044119611)
关键词
直肠肿瘤
淋巴结转移
淋巴化疗
药物聚集浓度
Rectal cancer
Lymph node metastasis
Lymphatic chemotherapy
Drug concentration
